Treatment with fennel ( " Foeniculum vulgare " ) has been associated with premature thelarche in several case reports.
2.
If no other changes of puberty or sex hormone effects occur, it is referred to as isolated premature thelarche, and generally requires no treatment.
3.
Therefore, hyperthyroidism, Cushing syndrome, precocious puberty in women with premature thelarche ( breast growth ), premature menarche ( beginning of menstrual function ), increased speed of growth and growth hormone excess can ensue.
4.
"' Premature thelarche "'is a rare medical condition that is characterized by isolated breast development ( thelarche being the onset of breast development ) at a very early age with no other signs of sexual maturation.
5.
Premature thelarche is distinct from neonatal breast hyperplasia ( see also witch's milk ), which is common in the first few months of life and is due to acute exposure to high levels of sex hormones like estrogen during pregnancy.
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